Friday, September 13, 2013

Novartis Warns Of Wrong Tablets In Pet Medicine Clomicalm Bottles




1/31/2012 6:38 AM ET
(RTTNews) – It’s been only a few days since the consumer health division of Swiss drug maker Novartis AG (NVS: News ) temporarily suspended operations at Lincoln, Nebraska, production facility and recalled certain over-the-counter drugs – Bufferin, Excedrin, Gas-X Prevention and NoDoz, due to mix-up of products. Now, the animal health division of Novartis has warned that a wrong tablet may be found in bottles of Clomicalm, which is prescribed to treat behavioral disorders in dogs.


READ MORE…………http://www.rttnews.com/1808841/novartis-warns-of-wrong-tablets-in-pet-medicine-clomicalm-bottles.aspx?type%C3%BDr








Some research I did on Glucosamine


(says it can cause liver damage)


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(Says liver damage is unlikely)


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(Forum discussion on this topic of does it or does it not)


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Questions for Dr. Shawn – Arthritis, Glucosamine, Supplements, Joint, Legs

http://www.petcarenaturally.com/ask-dr-shawn/arthritis-glucosamine-supplements-joint-legs.php 








<snip> In short, I do not recommend home medicating with aspirin. If your pet is in pain, contact your veterinarian. Together you can develop a comprehensive and well-thought-out pain management protocol.<snip>


Can Dogs Take Aspirin?


http://blogs.dogster.com/vet_blog_information_advice/can-dogs-take-aspirin/







Generic Name: methimazole
Dosage Form: tablet, sugar coated
Felimazole Coated Tablets
Methimazole


For oral use in cats only.


CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
Felimazole Description


Methimazole is a thioureylene antithyroid drug, which inhibits the synthesis of thyroid hormones. Methimazole (1-methylimidazole-2-thiol) is a white, crystalline substance that is freely soluble in water. The chemical formula is C4H6N2S. Molecular weight is 114.16.


SOURCE: Drugs.com
READ FULL ARTICLE HERE: http://www.drugs.com/pro/felimazole.html?printable=1


FELIMAZOLE – METHINAZOLE







Metoclopramide (Reglan)


Brand Name: Reglan


Available in 5 mg & 10 mg tablets (oral suspension exists but is famous for unpalatable taste to pets)


How This Medication Works


One of the stomach’s most important functions is to grind the food we eat into a fine slurry that passes freely through the intestines. A strong rhythm of contraction is necessary to affect this and this rhythm creates the stomach’s motility.


Motility disorders are common and may be chronic (of long duration) or of sudden onset. When motility is reduced in the stomach, food pools there and creates a sensation of nausea and bloating. In some cases, bile refluxes from the intestine back into the stomach, causing irritation and more nausea. Metoclopramide normalizes stomach contractions so that food and bile can pass in the correct direction.


An additional effect of metoclopramide is helpful in the control of nausea. There is a biochemical barrier separating the brain and central nervous system from the blood stream so that only certain biochemicals can cross over. This partition is called the blood-brain barrier. Metoclopramide is able to cross the blood-brain barrier and act on the brain directly to control the sensation of nausea.


Metoclopramide thus helps the vomiting patient by normalizing stomach motility and acting directly on the brain to reduce the sensation of nausea.


How This Medication Is Used


Signs of nausea in pets include:


* Loss of appetite
* Vomiting
* Drooling
* Loud stomach or intestinal sounds
* Chewing motions


Metoclopramide can be used to control nausea in any situation except in the event of stomach or intestinal obstruction. If a motility problem is suspected (a classical history would include vomiting food many hours after eating), metoclopramide should also be helpful. If a motility disorder extends beyond the stomach (for example, a colon motility disorder might lead to constipation), metoclopramide would not expected to be helpful.


METOCLOPRAMIDE IS BEST GIVEN 20 MINUTES BEFORE A MEAL.


Side Effects


Side effects are rare with metoclopramide but generally stem from the ability to penetrate the blood-brain barrier. Animals predisposed to seizures (i.e., epileptics)http://www.veterinarypartner.com/Content.plx?P=A&A=560&S=1&EVetID=0 may experience seizures, although this should not be a problem for normal animals.


Some animals experience drowsiness and others will experience marked hyperactivity. Hyperactivity can be reversed with a dose of Benedryl (diphenhydramine). http://www.veterinarypartner.com/Content.plx?P=A&A=551&S=1&EVetID=0


Constipation has been reported as a side effect in some individuals. This is not a common side effect.


If you suspect your pet is having an adverse reaction to metoclopramide, discontinue the medication and inform your veterinarian. There is another motility modifier called cisapride (Propulsid)
http://www.veterinarypartner.com/Content.plx?P=A&A=2014&S=1&EVetID=0 that may be a good alternative. This medication does not cross the blood-brain barrier and hence does not have the behavioral side effects that metoclopramide can, but it also does not reduce the sensation of nausea by this additional mechanism either.


Interactions With Other Medications


Metoclopramide should not be used with phenothiazine tranquilizers such as acepromazine
http://www.veterinarypartner.com/Content.plx?P=A&A=570&S=1&EVetID=0 if there is any potential for seizures in the patient. Both medications serve to lower the threshold to seizures.


Propantheline bromide (Pro-Banthine), which is used to treat some cardiac arrhythmias, will inactivate metoclopramide.


Narcotic analgesics may negate the effects of metoclopramide.


Cautions and Contraindications


In patients with pheochromocytoma (a rare adrenal tumor) the use of metoclopramide can induce dangerously high blood pressure.


If stomach obstruction is suspected in a patient, it is best not to encourage motility and some other anti-nausea drug is preferred.


Metoclopramide crosses the placenta and into milk and is probably best avoided in pregnant or nursing mothers


It is our policy not to give dosing information over the Internet.


SOURCE: The Pet Pharmacy
http://www.veterinarypartner.com/Content.plx?P=A&A=523&S=1


Date Published: 1/1/2001
Date Reviewed/Revised: 07/23/2007







Metronidazole (Flagyl)


SEE ATTACHMENT BELOW
Metronidazole


Generic Name: metronidazole (me troe NI da zole)
Brand Names: Flagyl, Flagyl 375, Flagyl ER


Metronidazole is an antibiotic used by veterinarians to treat various conditions such as inflammatory bowel disease, nonspecific diarrheal disorders, infections caused by Giardia and periodontal disease.


Tell your veterinarian if your pet is allergic to any medications, or if your pet has; liver disease; anemia; epilepsy; or nerve disorders.


Metronidazole is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to use this medication in dogs and cats.


Antibiotic medications can cause diarrhea, which may be the sign of a new infection. If your pet has diarrhea that is watery or has blood in it, call your veterinarian. Do not use any medication to stop the diarrhea unless your veterinarian tells you to.


Side Affects: Any signs of an allergic reaction (hives; difficulty breathing; swelling of the face, lips, tongue, or throat). Seizures; fever, chills; sores inside the mouth or on the lips; watery or bloody diarrhea. Keep giving Metronidazole and talk to your veterinarian if your pet develops any of these less serious side effects; nausea, diarrhea; dizziness, loss of balance; dry mouth; cough, sneezing, runny nose; swollen tongue.


Adverse Effects/Warnings – Adverse effects reported in dogs include neurologic disorders, lethargy, weakness, neutropenias, hepatotoxicity, hematuria, anorexia, nausea, vomit­ing and diarrhea.
Flagyl – Metronidazole is an antibiotic which is commonly used to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowel. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is rapidly absorbed from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria, it is commonly used with other antibiotics when it is used to treat mixed bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides, and some cephalosporins.


Dogs and Cats
Metronidazole is used to treat protozoal infections in cats and dogs including Giardia, Entamoeba, Trichomonas, and Balantidium. It is also used to treat anaerobic bacterial infections. Metronidazole has immune modulating activity and may be prescribed to treat inflammatory bowel disease. It may be used to treat colitis caused by other antibiotics, periodontal disease (especially in cats), Clostridium perfringens enterotoxemia, tetanus, diarrhea of undetermined cause, pancreatic insufficiency (with small intestinal bacterial overgrowth), and complications of severe liver disease. Metronidazole may be used with corticosteroids in the treatment of inflammatory bowel disease, or gum disease (gingivitis/stomatitis) in cats. Topical metronidazole gel is used in the treatment of skin infections, such as feline chin acne.


Metronidazole is usually tolerated better if given with food and there are a wide variety of flavors and preparations made by compounding pharmacies in order to deal with the problems associated with the bitter taste. Because of the variety of uses for this drug, dose amount, frequency and duration of treatment vary widely.


Most common: clinical signs related to the bad taste, or GI upset.


• Dogs and cats: excessive salivation, gagging, regurgitation, pawing at the mouth, nausea, vomiting, and decreased appetite are the most frequent complaints. Less common or rare side effects include diarrhea, depression, lethargy, weakness, low white blood cell count, liver failure, and blood in the urine, or dark urine due to pigment changes. Neurologic signs may be seen after accidental overdose or, more commonly, with long-term moderate to high-dose therapy as in the treatment of difficult bacterial infections. Signs often begin 7 to 12 days following the start of treatment.


Metronidazole is an antibiotic and antiprotozoal medication. It is used to treat diarrheal diseases, certain bacterial infections, Giardia infections, and inflammatory bowel disease (IBD). The tablets have a very bitter taste. The dose varies widely based on the condition being treated. Metronidazole can cause birth defects in some species. Contact your veterinarian if your pet experiences loss of appetite, vomiting, diarrhea, depression, weakness, blood in the urine, head tilt, disorientation, stumbling, or jaundice (yellowing of the gums, skin, or whites of the eyes) while being treated with metronidazole.







An impotence tablet is helping to keep a pet dog with a heart condition from an early grave.


Viagra helps heart condition dog


Talisker, a border collie, passes out when he gets excited


An impotence tablet is helping to keep a pet dog with a heart condition from an early grave.


Talisker, a border collie, was living on borrowed time after vets found his heart had become dangerously enlarged.


The dog, three, from Yardley Hastings, Northamptonshire, passes out when he gets excited because his blood cannot pump quickly enough around his body. But, since taking Viagra, the blood


READ ENTIRE ARTICLE
http://news.bbc.co.uk/2/hi/uk_news/england/northamptonshire/7307673.stm







(NaturalNews) Pfizer has launched a diet medication for dogs, drawing criticism from veterinarians and animal welfarists who believe that there are no pharmaceutical solutions to the problem of obesity in domestic animals.


Approximately one-quarter of dogs and one-third of cats in the United Kingdom are obese, as well as significant numbers of other pets including rabbits and hamsters. As in humans, obesity in pets increases the risk of cardiovascular disease, joint problems and diabetes; the prevalence of feline diabetes has increased fivefold in http://www.naturalnews.com/022795.html



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